Extracellular polymeric substance (EPS)-degrading enzymes reduce staphylococcal surface attachment and biocide resistance on pig skin in vivo.

Extracellular polymeric substance (EPS)-degrading enzymes reduce staphylococcal surface attachment and biocide resistance on pig skin in vivo.

Staphylococcal extracellular polymeric substances (EPS) such as extracellular DNA (eDNA) and poly-N-acetylglucosamine surface polysaccharide (PNAG) mediate numerous virulence traits including host colonization and antimicrobial resistance. Previous studies showed that EPS-degrading enzymes increase...

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Bibliographic Details
Main Authors: Jeffrey B Kaplan, Kevin D Mlynek, Hashani Hettiarachchi, Yonas A Alamneh, Lionel Biggemann, Daniel V Zurawski, Chad C Black, Charles E Bane, Robert K Kim, Mark S Granick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6179274?pdf=render

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http://europepmc.org/articles/PMC6179274?pdf=render

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