Roles of OX40 and OX40 Ligand in Mycosis Fungoides and Sézary Syndrome

Roles of OX40 and OX40 Ligand in Mycosis Fungoides and Sézary Syndrome

Mycosis fungoides (MF) and Sézary syndrome (SS), the most common types of cutaneous T-cell lymphoma (CTCL), are characterized by proliferation of mature CD4+ T-helper cells. Patients with advanced-stage MF and SS have poor prognosis, with 5-year survival rates of 52%. Although a variety of systemic...

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Bibliographic Details
Main Authors: Yuki Kawana, Hiraku Suga, Hiroaki Kamijo, Tomomitsu Miyagaki, Makoto Sugaya, Shinichi Sato
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
mycosis fungoides
Sézary syndrome
cutaneous T-cell lymphoma
OX40
TNF receptor superfamily
Online Access:https://www.mdpi.com/1422-0067/22/22/12576

Internet

https://www.mdpi.com/1422-0067/22/22/12576

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