An extended interaction site determines binding between AP180 and AP2 in clathrin mediated endocytosis

An extended interaction site determines binding between AP180 and AP2 in clathrin mediated endocytosis

Abstract The early phases of clathrin mediated endocytosis are organized through a highly complex interaction network mediated by clathrin associated sorting proteins (CLASPs) that comprise long intrinsically disordered regions (IDRs). AP180 is a CLASP exclusively expressed in neurons and comprises...

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Bibliographic Details
Main Authors: Samuel Naudi-Fabra, Carlos A. Elena-Real, Ida Marie Vedel, Maud Tengo, Kathrin Motzny, Pin-Lian Jiang, Peter Schmieder, Fan Liu, Sigrid Milles
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-50212-4

Internet

https://doi.org/10.1038/s41467-024-50212-4

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