Comparative RNA-Sequencing Analysis Reveals High Complexity and Heterogeneity of Transcriptomic and Immune Profiles in Hepatocellular Carcinoma Tumors of Viral (HBV, HCV) and Non-Viral Etiology

Comparative RNA-Sequencing Analysis Reveals High Complexity and Heterogeneity of Transcriptomic and Immune Profiles in Hepatocellular Carcinoma Tumors of Viral (HBV, HCV) and Non-Viral Etiology

<i>Background and Objectives</i>: Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, is the leading cause of cancer-related mortality. It arises and progresses against fibrotic or cirrhotic backgrounds mainly due to infection with hepatitis viruses B (HBV) or C...

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Bibliographic Details
Main Authors: Liliana Paslaru, Gabriela Bindea, Anca Nastase, Andrei Sorop, Cristian Zimbru, Vlad Herlea, Doina Hrehoret, Vlad Brasoveanu, Radu Zamfir, Simona Dima, Irinel Popescu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Medicina
Subjects:
hepatocellular carcinoma
HBV
HCV
RNA-seq
immune infiltrate
biomarkers
Online Access:https://www.mdpi.com/1648-9144/58/12/1803

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https://www.mdpi.com/1648-9144/58/12/1803

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