Odorant Receptor 51E2 Agonist β-ionone Regulates RPE Cell Migration and Proliferation

Odorant Receptor 51E2 Agonist β-ionone Regulates RPE Cell Migration and Proliferation

The odorant receptor 51E2 (OR51E2), which is well-characterized in prostate cancer cells and epidermal pigment cells, was identified for the first time as the most highly expressed OR in human fetal and adult retinal pigment epithelial (RPE) cells. Immunofluorescence staining and Western blot analys...

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Bibliographic Details
Main Authors: Nikolina Jovancevic, Soumaya Khalfaoui, Markus Weinrich, Daniel Weidinger, Annika Simon, Benjamin Kalbe, Marcus Kernt, Anselm Kampik, Günter Gisselmann, Lian Gelis, Hanns Hatt
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Physiology
Subjects:
GPCR
gene expression
cell signaling
calcium imaging
cell proliferation
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00888/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00888/full

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