Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism

Mitochondrial dysfunction is a hallmark of metabolic diseases such as obesity, type 2 diabetes mellitus, neurodegenerative diseases, and cancers. Dysfunction occurs in part because of altered regulation of the mitochondrial pyruvate dehydrogenase complex (PDC), which acts as a central metabolic node...

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Hlavní autoři: Sungmi Park, Jae-Han Jeon, Byong-Keol Min, Chae-Myeong Ha, Themis Thoudam, Bo-Yoon Park, In-Kyu Lee
Médium: Článek
Jazyk:English
Vydáno: Korean Diabetes Association 2018-08-01
Edice:Diabetes & Metabolism Journal
Témata:
On-line přístup:https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-42-270.pdf