Effects of RORγt overexpression on the murine central nervous system

Abstract Objective T helper 17 (Th17) cells are a subset of CD4+ T cells that produce interleukin (IL)‐17A. Recent studies showed that an increase in circulating IL‐17A causes cognitive dysfunction, although it is unknown how increased systemic IL‐17A affects brain function. Using transgenic mice ov...

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Bibliographic Details
Main Authors: Tetsuya Sasaki, Rei Nagata, Satoru Takahashi, Yosuke Takei
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Neuropsychopharmacology Reports
Subjects:
Online Access:https://doi.org/10.1002/npr2.12162