Quantifying carbon sources for de novo lipogenesis in wild-type and IRS-1 knockout brown adipocytes
Studies were conducted to evaluate the flux of various carbon sources to lipogenesis during brown adipocyte differentiation. 13C labeling and isotopomer spectral analysis quantified the contribution of metabolites to de novo lipogenesis in wild-type (WT) and insulin receptor substrate-1 knockout (KO...
Main Authors: | Hyuntae Yoo, Gregory Stephanopoulos, Joanne K. Kelleher |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2004-07-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520317880 |
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