Association between Genetic Variants in <i>NOS2</i> and <i>TNF</i> Genes with Congenital Zika Syndrome and Severe Microcephaly

Association between Genetic Variants in <i>NOS2</i> and <i>TNF</i> Genes with Congenital Zika Syndrome and Severe Microcephaly

Zika virus (ZIKV) causes Congenital Zika Syndrome (CZS) in individuals exposed prenatally. Here, we investigated polymorphisms in <i>VEGFA, PTGS2, NOS3, TNF</i>, and <i>NOS2</i> genes as risk factors to CZS. Forty children with CZS and forty-eight children who were in utero e...

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Bibliographic Details
Main Authors: Julia A. Gomes, Eduarda Sgarioni, Juliano A. Boquett, Ana Cláudia P. Terças-Trettel, Juliana H. da Silva, Bethânia F. R. Ribeiro, Marcial F. Galera, Thalita M. de Oliveira, Maria Denise F. Carvalho de Andrade, Isabella F. Carvalho, Lavínia Schüler-Faccini, Fernanda S. L. Vianna
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Viruses
Subjects:
maternal exposure
Zika virus
Zika virus infection
teratogens
congenital abnormalities
genetic variation
Online Access:https://www.mdpi.com/1999-4915/13/2/325

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https://www.mdpi.com/1999-4915/13/2/325

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