Cell-type-specific mRNA transcription and degradation kinetics in zebrafish embryogenesis from metabolically labeled single-cell RNA-seq

Cell-type-specific mRNA transcription and degradation kinetics in zebrafish embryogenesis from metabolically labeled single-cell RNA-seq

Abstract During embryonic development, pluripotent cells assume specialized identities by adopting particular gene expression profiles. However, systematically dissecting the relative contributions of mRNA transcription and degradation to shaping those profiles remains challenging, especially within...

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Bibliographic Details
Main Authors: Lior Fishman, Avani Modak, Gal Nechooshtan, Talya Razin, Florian Erhard, Aviv Regev, Jeffrey A. Farrell, Michal Rabani
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47290-9

Internet

https://doi.org/10.1038/s41467-024-47290-9

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