Assessment of Toxicological Perturbations and Variants of Pancreatic Islet Development in the Zebrafish Model

The pancreatic islets, largely comprised of insulin-producing beta cells, play a critical role in endocrine signaling and glucose homeostasis. Because they have low levels of antioxidant defenses and a high perfusion rate, the endocrine islets may be a highly susceptible target tissue of chemical ex...

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Bibliographic Details
Main Authors: Karilyn E. Sant, Haydee M. Jacobs, Jiali Xu, Katrina A. Borofski, Larry G. Moss, Jennifer B. Moss, Alicia R. Timme-Laragy
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Toxics
Subjects:
Online Access:http://www.mdpi.com/2305-6304/4/3/20