Sleep/Wake Disruption in a Mouse Model of BLOC-1 Deficiency

Sleep/Wake Disruption in a Mouse Model of BLOC-1 Deficiency

Mice lacking a functional Biogenesis of Lysosome-related Organelles Complex 1 (BLOC-1), such as those of the pallid line, display cognitive and behavioural impairments reminiscent of those presented by individuals with intellectual and developmental disabilities. Although disturbances in the sleep/w...

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Bibliographic Details
Main Authors: Frank Y. Lee, Huei-Bin Wang, Olivia N. Hitchcock, Dawn Hsiao Loh, Daniel S. Whittaker, Yoon-Sik Kim, Achilles Aiken, Collette Kokikian, Esteban C. Dell’Angelica, Christopher S. Colwell, Cristina A. Ghiani
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neuroscience
Subjects:
BLOC-1
sleep
circadian rhythms
dysbindin
pallidin
CREB
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00759/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00759/full

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