GDF15 Promotes the Osteogenic Cell Fate of Periodontal Ligament Fibroblasts, thus Affecting Their Mechanobiological Response

GDF15 Promotes the Osteogenic Cell Fate of Periodontal Ligament Fibroblasts, thus Affecting Their Mechanobiological Response

Periodontal ligament fibroblasts (PdLFs) exert important functions in oral tissue and bone remodeling following mechanical forces, which are specifically applied during orthodontic tooth movement (OTM). Located between the teeth and the alveolar bone, mechanical stress activates the mechanomodulator...

Full description

Bibliographic Details
Main Authors: Lukas Lösch, Albert Stemmler, Adrian Fischer, Julia Steinmetz, Lisa Schuldt, Christoph-Ludwig Hennig, Judit Symmank, Collin Jacobs
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
GDF15
orthodontic tooth movement
periodontal ligament fibroblasts
osteoblast differentiation
mechanobiological response
inflammation
Online Access:https://www.mdpi.com/1422-0067/24/12/10011

Internet

https://www.mdpi.com/1422-0067/24/12/10011

Similar Items