Rational Discovery of Antiviral Whey Protein-Derived Small Peptides Targeting the SARS-CoV-2 Main Protease

Rational Discovery of Antiviral Whey Protein-Derived Small Peptides Targeting the SARS-CoV-2 Main Protease

In the present work, and for the first time, three whey protein-derived peptides (IAEK, IPAVF, MHI), endowed with ACE inhibitory activity, were examined for their antiviral activity against the SARS-CoV-2 3C-like protease (3CL<sup>pro</sup>) and Human Rhinovirus 3C protease (3C<sup>...

Full description

Bibliographic Details
Main Authors: Nicola Gambacorta, Leonardo Caputo, Laura Quintieri, Linda Monaci, Fulvio Ciriaco, Orazio Nicolotti
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
antiviral peptides
protease inhibitors
molecular docking
rhinovirus
COVID-19
milk
Online Access:https://www.mdpi.com/2227-9059/10/5/1067

Internet

https://www.mdpi.com/2227-9059/10/5/1067

Similar Items