A Comprehensive Workflow of Mass Spectrometry-Based Untargeted Metabolomics in Cancer Metabolic Biomarker Discovery Using Human Plasma and Urine

Current available biomarkers lack sensitivity and/or specificity for early detection of cancer. To address this challenge, a robust and complete workflow for metabolic profiling and data mining is described in details. Three independent and complementary analytical techniques for metabolic profiling...

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Bibliographic Details
Main Authors: Jianwen She, Wei Zou, Vladimir V. Tolstikov
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Metabolites
Subjects:
Online Access:http://www.mdpi.com/2218-1989/3/3/787