The influence of antibiotic treatment on the behavior and gut microbiome of adult rats neonatally insulted with lipopolysaccharide

The present study investigated whether neonatal exposure to the proinflammatory endotoxin lipopolysaccharide (LPS) followed by an antibiotic (ATB)-induced dysbiosis in early adulthood could induce neurodevelopmental disorders-like behavioral changes in adult male rats. Combining these two stressors...

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Bibliographic Details
Main Authors: Hana Tejkalová, Lea Jakob, Simona Kvasnová, Jan Klaschka, Hana Sechovcová, Jakub Mrázek, Tomáš Páleníček, Kateřina Olša Fliegerová
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023026245