Breast cancer associated germline structural variants harboring small noncoding RNAs impact post-transcriptional gene regulation

Breast cancer associated germline structural variants harboring small noncoding RNAs impact post-transcriptional gene regulation

Abstract Copy Number Variants (CNVs) are a class of structural variations of DNA. Germline CNVs are known to confer disease susceptibility, but their role in breast cancer warrants further investigations. We hypothesized that breast cancer associated germline CNVs contribute to disease risk through...

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Bibliographic Details
Main Authors: Mahalakshmi Kumaran, Preethi Krishnan, Carol E. Cass, Roland Hubaux, Wan Lam, Yutaka Yasui, Sambasivarao Damaraju
Format: Article
Language:English
Published: Nature Portfolio 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25801-1

Internet

https://doi.org/10.1038/s41598-018-25801-1

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