Decreased circulating myeloid-derived suppressor cell count at the engraftment is one of the risk factors for multiple myeloma relapse after autologous hematopoietic stem cell transplantation

Decreased circulating myeloid-derived suppressor cell count at the engraftment is one of the risk factors for multiple myeloma relapse after autologous hematopoietic stem cell transplantation

Recent studies demonstrated that myeloid-derived suppressor cells (MDSCs) are involved in the pathogenesis and progression of multiple myeloma (MM). Nevertheless, data on the quantitative and functional changes in MDSCs during standard MM treatment remain poorly understood. Here, we determined that...

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Bibliographic Details
Main Authors: Tamara Tyrinova, Egor Batorov, Tatyana Aristova, Galina Ushakova, Svetlana Sizikova, Vera Denisova, Elena Chernykh
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Multiple myeloma
Myeloid-derived suppressor cells
Arginase-1
Hematopoietic stem cell transplantation
Lenalidomide
Immune recovery
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024023934

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http://www.sciencedirect.com/science/article/pii/S2405844024023934

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