Oxysterol 25-hydroxycholesterol activation of ferritinophagy inhibits the development of squamous intraepithelial lesion of cervix in HPV-positive patients

Abstract Squamous intraepithelial lesion of cervix (SIL) in human papillomavirus (HPV)-positive patient often undergoes a silent and long-course development, and most of them with high-grade transit to cervical squamous cell carcinoma (CSCC). The oxysterol 25-hydroxycholesterol (25-HC) is associated...

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Bibliographic Details
Main Authors: Tianming Wang, Min Gong, Yingfei Lu, Chengcheng Zhao, Ling Ling, Jianquan Chen, Rong Ju
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01899-3