Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo

Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo

After fertilization, remodeling of the oocyte and sperm genome is essential for the successful initiation of mitotic activity in the fertilized oocyte and subsequent proliferative activity of the early embryo. Despite the fact that the molecular mechanisms of cell cycle control in early mammalian em...

Full description

Bibliographic Details
Main Authors: Vladimír Baran, Alexandra Mayer
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
cleaving embryo
Chk1 kinase
cell cycle checkpoint
DNA damage
Online Access:https://www.mdpi.com/1422-0067/24/7/6778

Internet

https://www.mdpi.com/1422-0067/24/7/6778

Similar Items