C-Myc-induced hypersialylation of small cell lung cancer facilitates pro-tumoral phenotypes of macrophages

C-Myc-induced hypersialylation of small cell lung cancer facilitates pro-tumoral phenotypes of macrophages

Summary: Immunosuppressive myeloid cell populations have been documented in small cell lung cancer (SCLC) subtypes, playing a key role in remolding the tumor microenvironment (TME). However, the cancer-associated transcriptional features of monocytes and tumor-associated macrophages (TAMs) in SCLC r...

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Bibliographic Details
Main Authors: Lin Tian, Hui Li, Peiyan Zhao, Yan Liu, Yuanhua Lu, Rui Zhong, Yulong Jin, Tianyu Tan, Ying Cheng
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Biochemistry
Immunology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223018485

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http://www.sciencedirect.com/science/article/pii/S2589004223018485

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