S100A6 inhibits MDM2 to suppress breast cancer growth and enhance sensitivity to chemotherapy

Abstract Background S100A6 and murine double minute 2 (MDM2) are important cancer-related molecules. A previous study identified an interaction between S100A6 and MDM2 by size exclusion chromatography and surface plasmon resonance experiments. The present study investigated whether S100A6 could bind...

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Bibliographic Details
Main Authors: Mengxin Qi, Xianglan Yi, Baohui Yue, Mingxiang Huang, Sheng Zhou, Jing Xiong
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Breast Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13058-023-01657-w