IgG3 and IgM Identified as Key to SARS-CoV-2 Neutralization in Convalescent Plasma Pools

IgG3 and IgM Identified as Key to SARS-CoV-2 Neutralization in Convalescent Plasma Pools

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Analysis of convalescent plasma derived from individuals has shown that IgG3 has the most important role in binding to SARS-CoV-2 antigens; however, this has not yet been confirmed in large studies, and the link between binding and neutralization has not been confirmed. By analyzing plasma pools con...

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Bibliographic Details
Main Authors: Christina Kober, Sandro Manni, Svenja Wolff, Thomas Barnes, Shatanik Mukherjee, Thomas Vogel, Lea Hoenig, Peter Vogel, Aaron Hahn, Michaela Gerlach, Martin Vey, Eleonora Widmer, Björn Keiner, Patrick Schuetz, Nathan Roth, Uwe Kalina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726489/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726489/?tool=EBI

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