Ultrasmall PtMn nanoparticles as sensitive manganese release modulator for specificity cancer theranostics

Ultrasmall PtMn nanoparticles as sensitive manganese release modulator for specificity cancer theranostics

Abstract Manganese-based nanomaterials (Mn-nanomaterials) hold immense potential in cancer diagnosis and therapies. However, most Mn-nanomaterials are limited by the low sensitivity and low efficiency toward mild weak acidity (pH 6.4–6.8) of the tumor microenvironment, resulting in unsatisfactory th...

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Bibliographic Details
Main Authors: Guoqiang Guan, Huiyi Liu, Juntao Xu, Qingpeng Zhang, Zhe Dong, Lingling Lei, Cheng Zhang, Renye Yue, Hongchang Gao, Guosheng Song, Xian Shen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Ultrasmall alloy nanoparticle
Ultrasensitive
H2O2-free oxidase enzyme-like activity
High field magnetic resonance imaging
Ferroptosis
Online Access:https://doi.org/10.1186/s12951-023-02172-y

Internet

https://doi.org/10.1186/s12951-023-02172-y

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