Humoral responses to the measles, mumps and rubella vaccine are impaired in Leigh Syndrome French Canadian patients.

Humoral responses to the measles, mumps and rubella vaccine are impaired in Leigh Syndrome French Canadian patients.

Leigh Syndrome French Canadian (LSFC) is a rare autosomal recessive metabolic disorder characterized by severe lactic acidosis crises and early mortality. LSFC patients carry mutations in the Leucine Rich Pentatricopeptide Repeat Containing (LRPPRC) gene, which lead to defects in the respiratory cha...

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Bibliographic Details
Main Authors: Adrien Fois, Anne-Marie Boucher-Lafleur, Julie Thompson Legault, Christian Renaud, Charles Morin, Christine Des Rosiers, Lise Coderre, Catherine Laprise, Sylvie Lesage, LSFC Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0239860

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https://doi.org/10.1371/journal.pone.0239860

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