Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling

Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling

Abstract Chronic consumption of hyperpalatable and hypercaloric foods has been pointed out as a factor associated with cognitive decline and memory impairment in obesity. In this context, the integration between peripheral and central inflammation may play a significant role in the negative effects...

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Bibliographic Details
Main Authors: Roberta Ribeiro, Emanuele Guimarães Silva, Felipe Caixeta Moreira, Giovanni Freitas Gomes, Gabriela Reis Cussat, Barbara Stehling Ramos Silva, Maria Carolina Machado da Silva, Heliana de Barros Fernandes, Carolina de Sena Oliveira, Leonardo de Oliveira Guarnieri, Victoria Lopes, Cláudia Natália Ferreira, Ana Maria Caetano de Faria, Tatiani Uceli Maioli, Fabíola Mara Ribeiro, Aline Silva de Miranda, Grace Schenatto Pereira Moraes, Antônio Carlos Pinheiro de Oliveira, Luciene Bruno Vieira
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42955-9

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https://doi.org/10.1038/s41598-023-42955-9

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