Towards a Better Understanding of Verapamil Release from Kollicoat SR:IR Coated Pellets Using Non-Invasive Analytical Tools

Towards a Better Understanding of Verapamil Release from Kollicoat SR:IR Coated Pellets Using Non-Invasive Analytical Tools

The aim of this study was to gain deeper insight into the mass transport mechanisms controlling drug release from polymer-coated pellets using non-invasive analytical tools. Pellet starter cores loaded with verapamil HCl (10% loading, 45% lactose, 45% microcrystalline cellulose) were prepared by ext...

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Bibliographic Details
Main Authors: Julie Fahier, Branko Vukosavljevic, Laure De Kinder, Hugues Florin, Jean-François Goossens, Maike Windbergs, Florence Siepmann, Juergen Siepmann, Susanne Muschert
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
controlled release
coated pellet
polyvinyl acetate
weakly basic drug
drug release mechanisms
film coating
Online Access:https://www.mdpi.com/1999-4923/13/10/1723

Internet

https://www.mdpi.com/1999-4923/13/10/1723

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