The role of the interactome in the maintenance of deleterious variability in human populations

Abstract Recent genomic projects have revealed the existence of an unexpectedly large amount of deleterious variability in the human genome. Several hypotheses have been proposed to explain such an apparently high mutational load. However, the mechanisms by which deleterious mutations in some genes...

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Bibliographic Details
Main Authors: Luz Garcia‐Alonso, Jorge Jiménez‐Almazán, Jose Carbonell‐Caballero, Alicia Vela‐Boza, Javier Santoyo‐López, Guillermo Antiñolo, Joaquin Dopazo
Format: Article
Language:English
Published: Springer Nature 2014-09-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20145222