Production of nanostructured molecular liquids by supercritical CO2 processing
Stable molecular clusters of ibuprofen and naproxen were prepared in dry ice, by supersonic jet expansion of their supercritical CO2 drug formulations into a liquid nitrogen cooled collection vessel, with up to 80% yield. Mixing the “dry ice” in water, resulted in the solubilization of the clusters...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-01-01
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Series: | OpenNano |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352952016300123 |