CitH3: a reliable blood biomarker for diagnosis and treatment of endotoxic shock
Abstract Current biomarkers for sepsis are limited by their non-specificity, short half-life, and insensitive response to therapy. Recently, we have demonstrated that citrullinated histone H3(CitH3) is released into the blood from neutrophil extracellular traps(NETs) in response to severe infection,...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-09337-4 |