Designing miRNA-Based Synthetic Cell Classifier Circuits Using Answer Set Programming

Designing miRNA-Based Synthetic Cell Classifier Circuits Using Answer Set Programming

Cell classifier circuits are synthetic biological circuits capable of distinguishing between different cell states depending on specific cellular markers and engendering a state-specific response. An example are classifiers for cancer cells that recognize whether a cell is healthy or diseased based...

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Bibliographic Details
Main Authors: Katinka Becker, Hannes Klarner, Melania Nowicka, Heike Siebert
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Boolean modeling
Answer Set Programming
synthetic biology
miRNA profiles
cell classifier
breast cancer
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2018.00070/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2018.00070/full

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