In Silico Drug Repurposing for Anti-Inflammatory Therapy: Virtual Search for Dual Inhibitors of Caspase-1 and TNF-Alpha

In Silico Drug Repurposing for Anti-Inflammatory Therapy: Virtual Search for Dual Inhibitors of Caspase-1 and TNF-Alpha

Inflammation involves a complex biological response of the body tissues to damaging stimuli. When dysregulated, inflammation led by biomolecular mediators such as caspase-1 and tumor necrosis factor-alpha (TNF-alpha) can play a detrimental role in the progression of different medical conditions such...

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Bibliographic Details
Main Authors: Alejandro Speck-Planche, Valeria V. Kleandrova, Marcus T. Scotti
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
anti-inflammatory
caspase-1
COVID-19
cytokine storm
drug repurposing
MLP
Online Access:https://www.mdpi.com/2218-273X/11/12/1832

Internet

https://www.mdpi.com/2218-273X/11/12/1832

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