Computer-aided molecular modeling and structural analysis of the human centromere protein–HIKM complex

Computer-aided molecular modeling and structural analysis of the human centromere protein–HIKM complex

Abstract Background Protein–peptide and protein–protein interactions play an essential role in different functional and structural cellular organizational aspects. While Cryo-EM and X-ray crystallography generate the most complete structural characterization, most biological interactions exist in bi...

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Bibliographic Details
Main Authors: Henrietta Onyinye Uzoeto, Samuel Cosmas, Judith Nnedimkpa Ajima, Amarachukwu Vivian Arazu, Chizoba Maryann Didiugwu, Daniel Emmanuel Ekpo, Glory Omini Ibiang, Olanrewaju Ayodeji Durojaye
Format: Article
Language:English
Published: SpringerOpen 2022-08-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
CENP-HIKM
X-ray crystallography
Kinetochore
Protein–protein interaction
Molecular docking
Online Access:https://doi.org/10.1186/s43088-022-00285-1

Internet

https://doi.org/10.1186/s43088-022-00285-1

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