Enhanced Extraction of Blood and Tissue Time-Activity Curves in Cardiac Mouse FDG PET Imaging by Means of Constrained Nonnegative Matrix Factorization

We propose an enhanced method to accurately retrieve time-activity curves (TACs) of blood and tissue from dynamic 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) cardiac images of mice. The method is noninvasive and consists of using a constrained nonnegative matrix fac...

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Bibliographic Details
Main Authors: Otman Sarrhini, Pedro D’Orléans-Juste, Jacques A. Rousseau, Jean-François Beaudoin, Roger Lecomte
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2023/5366733