2213 Tumor suppressors p53 and ARF control oncogenic potential of triple-negative breast cancer cells by regulating RNA editing enzyme ADAR1

OBJECTIVES/SPECIFIC AIMS: Triple-negative breast cancer (TNBC) accounts for one-fifth of the breast cancer patient population. The heterogeneous nature of TNBC and lack of options for targeted therapy make its treatment a constant adventure. The deficiency of tumor suppressors p53 and ARF is one of...

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Bibliographic Details
Main Authors: Che-Pei Kung, Emily A. Bross, Catherine E. Kuzmicki, Michael Benjamin, Leonard B. Maggi, Jason D. Weber
Format: Article
Language:English
Published: Cambridge University Press 2018-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866118001437/type/journal_article