Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota

Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota

Streptococcus pneumoniae is the most frequent cause of community-acquired pneumonia. Endogenous host defense molecules such as peptidoglycan recognition protein 4 (PGLYRP4) might influence the course of this disease. To the best of our knowledge, there are no reports on the relevance of PGLYRP4 in p...

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Bibliographic Details
Main Authors: Alexander N. Dabrowski, Anshu Shrivastav, Claudia Conrad, Kassandra Komma, Markus Weigel, Kristina Dietert, Achim D. Gruber, Wilhelm Bertrams, Jochen Wilhelm, Bernd Schmeck, Katrin Reppe, Philippe D. N'Guessan, Sahar Aly, Norbert Suttorp, Torsten Hain, Janine Zahlten
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
infectious diseases
innate immunity
microbiome
peptidoglycan recognition proteins (PGRP
PGLYRP)
pneumococcal pneumonia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02106/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02106/full

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