Adiponectin Upregulates MiR-133a in Cardiac Hypertrophy through AMPK Activation and Reduced ERK1/2 Phosphorylation.

Adiponectin and miR-133a are key regulators in cardiac hypertrophy. However, whether APN has a potential effect on miR-133a remains unclear. In this study, we aimed to investigate whether APN could regulate miR-133a expression in Angiotensin II (Ang II) induced cardiac hypertrophy in vivo and in vit...

Full description

Bibliographic Details
Main Authors: Ying Li, Xiaojun Cai, Yuqing Guan, Lei Wang, Shuya Wang, Yueyan Li, Ying Fu, Xiaoyuan Gao, Guohai Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4741527?pdf=render