DNA methylation patterns of imprinting centers for H19, SNRPN, and KCNQ1OT1 in single-cell clones of human amniotic fluid mesenchymal stem cell

DNA methylation patterns of imprinting centers for H19, SNRPN, and KCNQ1OT1 in single-cell clones of human amniotic fluid mesenchymal stem cell

Objective: To test the hypothesis that human amniotic fluid mesenchymal stem cells contain a unique epigenetic signature in imprinting centers of H19, SNRPN, and KCNQ1OT1 during in vitro cell culture. Materials and Methods: By bisulfite genomic sequencing, we analyzed the imprinting centers of three...

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Bibliographic Details
Main Authors: Hsiu-Huei Peng, Shuenn-Dyh Chang, An-Shine Chao, Chao-Nin Wang, Po-Jen Cheng, Shiaw-Min Hwang, Tzu-Hao Wang
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
amniotic fluid mesenchymal stem cell
DNA methylation
human imprinting gene
single-cell clones
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455912001180

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http://www.sciencedirect.com/science/article/pii/S1028455912001180

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