An Update on Protein Kinases as Therapeutic Targets—Part II: Peptides as Allosteric Protein Kinase C Modulators Targeting Protein–Protein Interactions

An Update on Protein Kinases as Therapeutic Targets—Part II: Peptides as Allosteric Protein Kinase C Modulators Targeting Protein–Protein Interactions

Human protein kinases are highly-sought-after drug targets, historically harnessed for treating cancer, cardiovascular disease, and an increasing number of autoimmune and inflammatory conditions. Most current treatments involve small molecule protein kinase inhibitors that interact orthosterically w...

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Bibliographic Details
Main Authors: Mulate Zerihun, Samuel J. S. Rubin, Shmuel Silnitsky, Nir Qvit
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
kinases
protein kinase C
allosteric
peptides
peptidomimetics
modified peptides
Online Access:https://www.mdpi.com/1422-0067/24/24/17504

Internet

https://www.mdpi.com/1422-0067/24/24/17504

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