Cancer Immunotherapy: Silencing Intracellular Negative Immune Regulators of Dendritic Cells

Dendritic cells (DCs) are capable of activating adaptive immune responses, or inducing immune suppression or tolerance. In the tumor microenvironment, the function of DCs is polarized into immune suppression that attenuates the effect of T cells, promoting differentiation of regulatory T cells and s...

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Bibliographic Details
Main Authors: Yao-Hua Liu, I-Jeng Yeh, Ming-Derg Lai, Kuan-Ting Liu, Po-Lin Kuo, Meng-Chi Yen
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/11/1/108