Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma

Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma

<p>Abstract</p> <p>Background</p> <p>N-acetyltransferase 1 (NAT1) and 2 (NAT2) are polymorphic isoenzymes responsible for the metabolism of numerous drugs and carcinogens. Acetylation catalyzed by NAT1 and NAT2 are important in metabolic activation of arylamines to elec...

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Bibliographic Details
Main Authors: Cobbs Gary A, Hein David W, Doll Mark A, Martini Benjamin D, Crawford Nigel PS, Colliver Daniel W, Mahid Suhal S, Petras Robert E, Galandiuk Susan
Format: Article
Language:English
Published: BMC 2007-05-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/8/28

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http://www.biomedcentral.com/1471-2350/8/28

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