Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for clinical applications

Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for clinical applications

Malignant pleural mesothelioma (MPM) is a rare and aggressive form of cancer. Here, the authors show MPM is heterogeneously composed of epithelioid and sarcomatoid components and their proportions associate with prognosis and could inform therapeutic strategies.

Bibliographic Details
Main Authors: Yuna Blum, Clément Meiller, Lisa Quetel, Nabila Elarouci, Mira Ayadi, Danisa Tashtanbaeva, Lucile Armenoult, François Montagne, Robin Tranchant, Annie Renier, Leanne de Koning, Marie-Christine Copin, Paul Hofman, Véronique Hofman, Henri Porte, Françoise Le Pimpec-Barthes, Jessica Zucman-Rossi, Marie-Claude Jaurand, Aurélien de Reyniès, Didier Jean
Format: Article
Language:English
Published: Nature Portfolio 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09307-6

Internet

https://doi.org/10.1038/s41467-019-09307-6

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