Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors
<p>Abstract</p> <p>Background</p> <p>Betulinic acid (BA) inhibits growth of several cancer cell lines and tumors and the effects of BA have been attributed to its mitochondriotoxicity and inhibition of multiple pro-oncogenic factors. Previous studies show that BA induce...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-08-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/11/371 |