Immunostimulatory effects on THP-1 cells by peptide or protein pharmaceuticals associated with injection site reactions

Injection site reaction (ISR) is a common side-effect associated with the use of peptide or protein pharmaceuticals. These types of pharmaceuticals-induced activation of antigen-presenting cells is assumed to be a key step in the pathogenesis of immune-mediated ISR. The present study was designed to...

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Bibliographic Details
Main Authors: Eri Hamamura-Yasuno, Tetsuo Aida, Yoshimi Tsuchiya, Kazuhiko Mori
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Immunotoxicology
Subjects:
Online Access:http://dx.doi.org/10.1080/1547691X.2020.1727071