Biological Evaluation and Transcriptomic Analysis of Corylin as an Inhibitor of Osteoclast Differentiation

Biological Evaluation and Transcriptomic Analysis of Corylin as an Inhibitor of Osteoclast Differentiation

Corylin, a flavonoid isolated from the fruit of <i>Psoralea corylifolia</i>, has an osteogenic effect on osteoblasts in vitro and bone micromass ex vivo. However, the effect and mechanism of corylin in regulating osteoclastogenesis remain unknown. By using murine bone marrow macrophages...

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Bibliographic Details
Main Authors: Anna Xiao-Dan Yu, Jian Xiao, Shi-Zheng Zhao, Xiang-Peng Kong, Kenneth Kin-Leung Kwan, Brody Zhong-Yu Zheng, Kevin Qi-Yun Wu, Tina Ting-Xia Dong, Karl Wah-Keung Tsim
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
corylin
osteoclast
RANKL
transcriptomics
signaling pathway
Online Access:https://www.mdpi.com/1422-0067/22/7/3540

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https://www.mdpi.com/1422-0067/22/7/3540

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