Emerging non-antibody‒drug conjugates (non-ADCs) therapeutics of toxins for cancer treatment

Emerging non-antibody‒drug conjugates (non-ADCs) therapeutics of toxins for cancer treatment

The non-selective cytotoxicity of toxins limits the clinical relevance of the toxins. In recent years, toxins have been widely used as warheads for antibody‒drug conjugates (ADCs) due to their efficient killing activity against various cancer cells. Although ADCs confer certain targeting properties...

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Bibliographic Details
Main Authors: Xiaolan Xu, Jiaming Zhang, Tao Wang, Jing Li, Yukang Rong, Yanfang Wang, Chenxia Bai, Qing Yan, Xiaohua Ran, Yingli Wang, Tianhong Zhang, Jin Sun, Qikun Jiang
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Toxins
Non-antibody‒drug conjugates
Delivery strategies
Prodrugs
Nano drug delivery systems
Biomimetic drug delivery systems
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523004525

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http://www.sciencedirect.com/science/article/pii/S2211383523004525

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