Evaluation of early left-sided cardiac reverse remodeling under combined therapy of sacubitril-valsartan and spironolactone compared with angiotensin-converting enzyme inhibitors and spironolactone

Evaluation of early left-sided cardiac reverse remodeling under combined therapy of sacubitril-valsartan and spironolactone compared with angiotensin-converting enzyme inhibitors and spironolactone

We aimed to compare therapies of sacubitril/valsartan + spironolactone (S/V + S) with angiotensin-converting enzyme inhibitors + spironolactone (ACEI + S) on the left-sided cardiac reverse remodeling (L-CRR). The second objective was to analyze the usefulness of GLS and LVEF in response to therapy.M...

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Bibliographic Details
Main Authors: Wioletta Sacharczuk, Rafał Dankowski, Stefan Ożegowski, Maciej Rojna, Andrzej Szyszka
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
sacubitril-valsartan
spironolactone
cardiac reverse remodeling
global longitudinal strain
left ventricular ejection fraction
indexed left atrial volume
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1103688/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1103688/full

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