HMGB1 mediates endogenous TLR2 activation and brain tumor regression.

HMGB1 mediates endogenous TLR2 activation and brain tumor regression.

<h4>Background</h4>Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor that carries a 5-y survival rate of 5%. Attempts at eliciting a clinically relevant anti-GBM immune response in brain tumor patients have met with limited success, which is due to brain immune pri...

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Bibliographic Details
Main Authors: James F Curtin, Naiyou Liu, Marianela Candolfi, Weidong Xiong, Hikmat Assi, Kader Yagiz, Matthew R Edwards, Kathrin S Michelsen, Kurt M Kroeger, Chunyan Liu, A K M Ghulam Muhammad, Mary C Clark, Moshe Arditi, Begonya Comin-Anduix, Antoni Ribas, Pedro R Lowenstein, Maria G Castro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Medicine
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19143470/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19143470/?tool=EBI

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