Prostate cancer genetic risk and associated aggressive disease in men of African ancestry

Abstract African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet, genetic studies have largely been conducted outside the context of Sub-Saharan Africa, identifying 278 common risk variants contributing to a multiethnic polygenic risk score, with rare variants foc...

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Bibliographic Details
Main Authors: Pamela X. Y. Soh, Naledi Mmekwa, Desiree C. Petersen, Kazzem Gheybi, Smit van Zyl, Jue Jiang, Sean M. Patrick, Raymond Campbell, Weerachai Jaratlerdseri, Shingai B. A. Mutambirwa, M. S. Riana Bornman, Vanessa M. Hayes
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43726-w