Crystal Structure of Allantoinase from <i>Escherichia coli</i> BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis

Crystal Structure of Allantoinase from <i>Escherichia coli</i> BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis

Allantoinase (ALLase; EC 3.5.2.5) possesses a binuclear metal center in which two metal ions are bridged by a posttranslationally carbamylated lysine. ALLase acts as a key enzyme for the biogenesis and degradation of ureides by catalyzing the conversion of allantoin into allantoate. Biochemically, A...

Full description

Bibliographic Details
Main Authors: Yen-Hua Huang, Po-Chun Yang, En-Shyh Lin, Ya-Yeh Ho, Wei-Feng Peng, Hsin-Pin Lu, Chien-Chih Huang, Cheng-Yang Huang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
allantoinase
hydantoinase
dihydropyrimidinase
active site loop
industrial enzyme
Online Access:https://www.mdpi.com/1420-3049/28/2/827

Internet

https://www.mdpi.com/1420-3049/28/2/827

Similar Items